Adrenocortical steroid metabolism and adrenal cortical function in liver disease.
نویسنده
چکیده
منابع مشابه
Expression and function of endocannabinoid receptors in the human adrenal cortex.
Endogenous cannabinoids are important signaling molecules in neuroendocrine control of homeostatic and reproductive functions including stress response and energy metabolism. The hypothalamic paraventricular and supraoptic nuclei have been shown to release endocannabinoids, which act as retrograde messengers to modulate the synaptic release of glutamate during stress response. This study endeav...
متن کاملAdrenocortical carcinoma secreting cortisol, androgens and aldosterone: a case report
INTRODUCTION Adrenocortical carcinoma is a rare malignancy with a poor prognosis and presents with mass effects and less often with signs of hormone excess (approximately 60% of all adrenocortical carcinoma's). Hormonally active adrenocortical carcinomas most commonly secrete cortisol while the co-secretion of multiple steroid hormones is rare. CASE PRESENTATION We report the case of a 59 yea...
متن کاملThe role of the liver and the adrenal in producing elevated plasma 17-hydroxycorticosteroid levels in surgery.
In another paper of this series (1) it was demonstrated that most patients undergoing surgery developed increased plasma levels of 17-hydroxycorticosteroids. Evidence was presented that these rises are mediated in part by extra-adrenal factors. The concept that extra-adrenal factors may affect adrenal steroid levels is not a new one but little evidence to support such a concept has been present...
متن کاملNonfunctional Adrenocortical Carcinoma with Foci of Osseous Metaplasia in a Young Girl
Nonfunctional adrenocortical carcinoma is an extremely rare malignant tumor in children. Unlike the functional tumor which is detected early due to its hormonal presentation, nonfunctional tumor is detected at a later stage. Here we report a case of a 10 year old girl who presented with abdominal mass and symptoms of short duration. No hypertension and cushingoid features were seen. Serum alpha...
متن کاملUse of urinary steroid profiling for diagnosing and monitoring adrenocortical tumours.
It has been suggested that urinary steroid profiling may be used to provide information aiding the diagnosis and monitoring of adrenocortical carcinoma. Nonetheless, the abnormal patterns suggestive of adrenal malignancy are not well defined. We retrospectively studied the urinary steroid profiles of five patients with adrenocortical carcinoma at presentation and at follow-up, and compared thes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The Journal of clinical investigation
دوره 39 شماره
صفحات -
تاریخ انتشار 1960